If you're using Groupwise as a mail client, you can usually add some mail rules just from your desktop.
Within the Groupwise main window, click Tools from the grey menu at the top. A Rules window will open:

We need to setup at least two rules - one for incoming mail, and one for outgoing. Also, it can be desirable to use a rule to clean-up the forwarded items from your sent-items folder, since Groupwise likes to make copies of things there too.
Once you've clicked New from the Rules window, you can enter some details for the new rule.

This rule tells Groupwise to forward any mail you receive to Affinity. If Affinity recognises the email address of the sender as being a client, it will record the email appropriately, otherwise the mail is ignored.
Back on the Rules window, click New:

This process means any mail you send will be forwarded to AffinityLive, where a special process looks at the recipient and subject, and if recognised, will file the email appropriately.
If Groupwise is keeping copies of the forwarded items in your sent folder, you can create another rule which says:

This ensures that those automatically forwarded mails don't fill up your Sent box.
And that's all you need to complete the email integration!